关键词 |
一抗 |
面向地区 |
剂型 |
其他 |
中文名称: 兔抗DEPTOR多克隆抗体
英文名称:Anti-DEPTOR rabbit polyclonal antibody
别 名: DEP.6; DEPDC6
抗 原: DEPTOR
相关类别:一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
反应种属:Human, Mouse
标 记 物:Unconjugate
克隆类型:rabbit polyclonal
技术规格
Background: | DEPTOR (DEP domain containing MTOR-interacting protein), also known as DEP.6 or DEPDC6 (DEP domain-containing protein 6), is a 409 amino acid protein that negatively regulates mTORC1 and mTORC2 pathways. DEPTOR interacts with FRAP via its PDZ domain, and undergoes post-translational phosphorylation. Containing two DEP domains and one PDZ (DHR) domain, DEPTOR is encoded by a gene that maps to human chromosome 8q24.12. Chromosome 8 consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8. |
Applications: | ELISA, WB, IHC |
Name of antibody: | DEPTOR |
Immunogen: | Synthetic peptide of human DEPTOR |
Full name: | DEP domain containing MTOR-interacting protein |
Synonyms: | DEP.6; DEPDC6 |
SwissProt: | Q8TB45 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human thyroid cancer;Human liver cancer |
IHC Recommend dilution: | 25-100 |
WB Predicted band size: | 46 kDa |
WB Positive control: | Human fetal liver tissue lysate |
WB Recommended dilution: | 200-1000 |
乌海本地兔抗DEPTOR热销信息